R. Mac Holbert, along with musician/photographer Graham Nash, in 1989 co-founded Nash Editions, widely regarded as the world's first digital printmaking studio focusing solely on photography.
In 2011, Mac established The Image Collective, to provide digital expertise to the cultural heritage world. In 2016, together with four other partners, Mac founded Art Authority, a company that provides extreme quality reproductions to museums.
Mac has lectured extensively on digital output, digital imaging/scanning, and fine art. He is a partner in plug-in provider PixelGenius, as well as a beta tester for Epson America, Canon, X-rite, NEC, Adobe, and other software and hardware manufacturers. Mac’s clients have included David Hockney, Steve McCurry, Douglas Kirkland, Jay Maisel, Pete Turner, Amy Toensing, Olivia Parker, Danny Lyon, Stephen Wilkes, Maggie Taylor, Stephen Shore, and Greg Gorman.